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ITGA2 antibody
ITGA2
Reactivity: Human
FACS, IHC, CoSt
Host: Mouse
Monoclonal
P1E6-C5
unconjugated
Product Details anti-ITGA2 Antibody
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Target
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ITGA2
(Integrin alpha 2 (ITGA2))
Reactivity
All reactivities for ITGA2 antibodies
Human
Host
All hosts for ITGA2 antibodies
Mouse
Clonality
All clonalities for ITGA2 antibodies
Monoclonal
Conjugate
All conjugates for ITGA2 antibodies
This ITGA2 antibody is un-conjugated
Application
All applications for ITGA2 antibodies
Flow Cytometry (FACS), Immunohistochemistry (IHC), Co-Stimulation (CoSt)
Purification
The antibody was purified by affinity chromatography.
Clone
P1E6-C5
Isotype
IgG1 kappa
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Discover our top product ITGA2 Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for ITGA2
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Target
ITGA2
(Integrin alpha 2 (ITGA2))
Alternative Name
CD49b (ITGA2 Products )
Synonyms
BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
Background
CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.
Pathways
CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Integrin Complex
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