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CXCR7 antibody
CXCR7
Reactivity: Human, Mouse
FACS
Host: Mouse
Monoclonal
8F11-M16
unconjugated
Product Details anti-CXCR7 Antibody
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Target
See all CXCR7 Antibodies
CXCR7
(Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
Reactivity
All reactivities for CXCR7 antibodies
Human, Mouse
Host
All hosts for CXCR7 antibodies
Mouse
Clonality
All clonalities for CXCR7 antibodies
Monoclonal
Conjugate
All conjugates for CXCR7 antibodies
This CXCR7 antibody is un-conjugated
Application
All applications for CXCR7 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
8F11-M16
Isotype
IgG2b kappa
Top Product
Discover our top product CXCR7 Primary Antibody
Alternatives
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anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Extracellular Domain) antibody
CXCR7
Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Bat, Rabbit, Hamster
IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CXCR7
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Target
CXCR7
(Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
Alternative Name
CXCR7 (CXCR7 Products )
Synonyms
CMKOR1 antibody, CXC-R7 antibody, CXCR-7 antibody, CXCR7 antibody, GPR159 antibody, RDC-1 antibody, RDC1 antibody, AW541270 antibody, Cmkor1 antibody, Cxcr7 antibody, Rdc1 antibody, ackr3 antibody, cxcr7 antibody, rdc1 antibody, xcxcr7 antibody, atypical chemokine receptor 3 antibody, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 antibody, atypical chemokine receptor 3 L homeolog antibody, ACKR3 antibody, MmrVgp88 antibody, Ackr3 antibody, ackr3.L antibody
Background
CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and other cell types.
Pathways
Myometrial Relaxation and Contraction , Negative Regulation of intrinsic apoptotic Signaling
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