cDNA Sequence AF251705 (AF251705) antibody

Details for Product No. ABIN2665259, Supplier: Log in to see
Antigen
  • CLM4
  • Cd300c
  • Cd300d
  • DIgR1
  • Igsf7
  • Lmir2
  • MAIR-II
  • cDNA sequence AF251705
  • AF251705
Reactivity
Human
2
Host
Mouse
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
1
Application
Flow Cytometry (FACS)
1
1
1
1
1
1
Options
Supplier
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Clone TX45
Isotype IgG1 kappa
Purification The antibody was purified by affinity chromatography.
Alternative Name MAIR-II (AF251705 Antibody Abstract)
Background MAIR-II, myeloid-associated immunoglobulin-like receptor II, is the member 7 of Ig superfamily (IgSF7), also known as LMIR-II, CMRF-35 like molecule 4 (CLM-4), DIgR1, and CD300d. This transmembrane protein is expressed on monocytes/macrophages, granulocytes, mast cells, dendritic cells and some B cells. It is an activating immune receptor associated ITAM-bearing adapter DAP12 and FcRγ chain on macrophages. MAIR-II regulates myeloid cell activation and promotes secretion of cytokines and chemokines
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-cDNA Sequence AF251705 (AF251705) antibody (ABIN2665259) anti-cDNA Sequence AF251705 (AF251705) antibody
Background publications Nakahashi, Tahara-Hanaoka, Totsuka, Okoshi, Takai, Ohkohchi, Honda, Shibuya, Shibuya: "Dual assemblies of an activating immune receptor, MAIR-II, with ITAM-bearing adapters DAP12 and FcRgamma chain on peritoneal macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 2, pp. 765-70, 2007 (PubMed).

Yotsumoto, Okoshi, Shibuya, Yamazaki, Tahara-Hanaoka, Honda, Osawa, Kuroiwa, Matsuda, Tenen, Iwama, Nakauchi, Shibuya: "Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation." in: The Journal of experimental medicine, Vol. 198, Issue 2, pp. 223-33, 2003 (PubMed).

Luo, Zhang, Sui, Li, Zhang, Ma, Zhang, Cao: "DIgR1, a novel membrane receptor of the immunoglobulin gene superfamily, is preferentially expressed by antigen-presenting cells." in: Biochemical and biophysical research communications, Vol. 287, Issue 1, pp. 35-41, 2001 (PubMed).

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