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SYK antibody (AA 5-360)
SYK
Reactivity: Human, Mouse, Rat
FACS
Host: Mouse
Monoclonal
SYK-01
unconjugated
Product Details anti-SYK Antibody
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Target
See all SYK Antibodies
SYK
(Spleen tyrosine Kinase (SYK))
Binding Specificity
All epitopes for SYK antibodies
AA 5-360
Reactivity
All reactivities for SYK antibodies
Human, Mouse, Rat
Host
All hosts for SYK antibodies
Mouse
Clonality
All clonalities for SYK antibodies
Monoclonal
Conjugate
All conjugates for SYK antibodies
This SYK antibody is un-conjugated
Application
All applications for SYK antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Immunogen
AA 5-360 human Syk
Clone
SYK-01
Isotype
IgG1 kappa
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Discover our top product SYK Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for SYK
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Target
SYK
(Spleen tyrosine Kinase (SYK))
Alternative Name
Syk (SYK Products )
Synonyms
p72-Syk antibody, Sykb antibody, p72syk antibody, spleen associated tyrosine kinase antibody, spleen tyrosine kinase antibody, syk antibody, SYK antibody, Syk antibody
Background
Syk is a cytoplasmic 72 kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites. The SYK-01 monoclonal antibody (raised against amino acids 5-360 of human Syk) recognizes human, mouse, and rat and Syk and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry.
Pathways
Fc-epsilon Receptor Signaling Pathway , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Thromboxane A2 Receptor Signaling , BCR Signaling
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