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ATIC antibody
ATIC
Reactivity: Human, Mouse, Rat, Drosophila melanogaster, Frog
BCA
Host: Mouse
Monoclonal
F38P7H9
unconjugated
Product Details anti-ATIC Antibody
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Target
See all ATIC Antibodies
ATIC
(5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
Reactivity
All reactivities for ATIC antibodies
Human, Mouse, Rat, Drosophila melanogaster, Frog
Host
All hosts for ATIC antibodies
Mouse
Clonality
All clonalities for ATIC antibodies
Monoclonal
Conjugate
All conjugates for ATIC antibodies
This ATIC antibody is un-conjugated
Application
All applications for ATIC antibodies
Biochemical Assay (BCA)
Purification
The antibody was purified by affinity chromatography.
Clone
F38P7H9
Isotype
IgG1 kappa
Top Product
Discover our top product ATIC Primary Antibody
Alternatives
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anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibody
ATIC
Reactivity: Human, Dog, Rabbit, Horse, Cow, Pig, Drosophila melanogaster, Monkey, Xenopus laevis
WB, IHC, IHC (p)
Host: Mouse
Monoclonal
F38 P7 H9
unconjugated
anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) (AA 379-428) antibody
ATIC
Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Pig, Guinea Pig, Hamster, Bat
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Upon receipt, store undiluted between 2°C and 8°C.
Target Details for ATIC
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Target
ATIC
(5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
Alternative Name
ATIC (ATIC Products )
Synonyms
AICAR antibody, AICARFT antibody, IMPCHASE antibody, PURH antibody, purH antibody, 2610509C24Rik antibody, AA536954 antibody, AW212393 antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog antibody, bifunctional purine biosynthesis protein PurH antibody, bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein PurH antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody, atic.L antibody, purH antibody, ATIC antibody, Atic antibody
Background
ATIC (AICAR transformylase/IMP cyclohydrolase) belongs to the purH family, expressed in the cytoplasm, predicted molecular weight approximately 65 kD. ATIC catalyzes the penultimate and final steps in the de novo purine nucleotide biosynthesis pathway. ATIC acts as a bifunctional enzyme catalyze the formation of FAICAR and IMP. AICA-ribosiduria is a recently discovered inherited metabolic disease caused by a defect in final steps of purine de novo biosynthesis. Clone F38P7H9 has been shown to be useful for western blotting and immunohistochemistry of human, mouse, rat, frog and fruit fly ATIC.
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