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NCR1 antibody (Alexa Fluor 647)
NCR1
Reactivity: Human
WB, ELISA, IHC, Func, Neut
Host: Mouse
Monoclonal
9E2
Alexa Fluor 647
Product Details anti-NCR1 Antibody (Alexa Fluor 647)
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Target
See all NCR1 Antibodies
NCR1
(Natural Cytotoxicity Triggering Receptor 1 (NCR1))
Reactivity
All reactivities for NCR1 antibodies
Human
Host
All hosts for NCR1 antibodies
Mouse
Clonality
All clonalities for NCR1 antibodies
Monoclonal
Conjugate
All conjugates for NCR1 antibodies
This NCR1 antibody is conjugated to Alexa Fluor 647
Application
All applications for NCR1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Functional Studies (Func), Neutralization (Neut)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
9E2
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target Details for NCR1
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Target
NCR1
(Natural Cytotoxicity Triggering Receptor 1 (NCR1))
Alternative Name
CD335 (NCR1 Products )
Synonyms
CD335 antibody, LY94 antibody, NK-p46 antibody, NKP46 antibody, Ly94 antibody, NKp46 antibody, KILR-1 antibody, Nk-p46 antibody, Nkp46 antibody, natural cytotoxicity triggering receptor 1 antibody, NCR1 antibody, Ncr1 antibody
Background
CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is direct-ly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
Pathways
Regulation of Leukocyte Mediated Immunity
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