NFKBIZ antibody (C-Term)
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- Target See all NFKBIZ Antibodies
- NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Goat, Guinea Pig, Sheep, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFKBIZ antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VRLLMRKGAD PSTRNLENEQ PVHLVPDGPV GEQIRRILKG KSIQQRAPPY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
- Characteristics
- This is a rabbit polyclonal antibody against Nfkbiz. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product NFKBIZ Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 728 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
- Alternative Name
- Nfkbiz (NFKBIZ Products)
- Synonyms
- RGD1310834 antibody, NFKBIZ antibody, MAIL antibody, AA408868 antibody, INAP antibody, Mail antibody, IKBZ antibody, NFKB inhibitor zeta antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta antibody, Nfkbiz antibody, NFKBIZ antibody, nfkbiz antibody
- Background
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Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
Alias Symbols: AA408868, INAP, Mail
Protein Interaction Partner: Nfkb2, Nfkb1, Ikbkg, Elf5, Ehf, Il6,
Protein Size: 728 - Molecular Weight
- 80 kDa
- Gene ID
- 80859
- NCBI Accession
- NM_030612, NP_085115
- UniProt
- Q9EST8
- Pathways
- NF-kappaB Signaling
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