UACA antibody (C-Term)
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- Target See all UACA Antibodies
- UACA
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UACA antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TELLNDVERL KQALNGLSQL TYTSGNPTKR QSQLIDTLQH QVKSLEQQLA
- Predicted Reactivity
- Cow: 100%, Dog: 85%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against UACA. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product UACA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1403 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- UACA
- Alternative Name
- UACA (UACA Products)
- Synonyms
- NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody
- Background
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UACA regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. It promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. It regulates the redistribution of APAF1 into the nucleus after proapoptotic stress and down-regulates the expression of LGALS3 by inhibiting NFKB1.
Alias Symbols: FLJ10128, KIAA1561, MGC141967, MGC141969, NUCLING
Protein Interaction Partner: KRT40, FUS, RNF2, HIF1AN, PAN2, TP63, UBC, USP48, RABEP1, STAMBP, FBXO25, NRD1, Mprip, MED14, CELSR3,
Protein Size: 1403 - Molecular Weight
- 154 kDa
- Gene ID
- 55075
- NCBI Accession
- NM_001008224, NP_001008225
- UniProt
- Q9BZF9
- Pathways
- Positive Regulation of Endopeptidase Activity
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