UACA antibody (AA 1-90)

Catalog No. ABIN7175186

Product Details anti-UACA Antibody

Target: UACA

Binding Specificity: AA 1-90

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UACA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (1-90AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UACA

Target: UACA

Alternative Name: UACA (UACA Products)

Synonyms: NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody

Background:

Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

Aliases: FLJ10128 antibody, KIAA1561 antibody, MGC141967 antibody, MGC141969 antibody, Nuclear membrane binding protein antibody, NUCLING antibody, UACA antibody, UACA_HUMAN antibody, Uveal autoantigen with coiled coil domains and ankyrin repeats antibody, Uveal autoantigen with coiled-coil domains and ankyrin repeats antibody

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity