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PDGFA antibody (C-Term)
PDGFA
Reactivity: Human, Mouse, Rat, Dog, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDGFA Antibody
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Target
See all PDGFA Antibodies
PDGFA
(Platelet Derived Growth Factor A (PDGFA))
Binding Specificity
All epitopes for PDGFA antibodies
C-Term
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig
Host
All hosts for PDGFA antibodies
Rabbit
Clonality
All clonalities for PDGFA antibodies
Polyclonal
Conjugate
All conjugates for PDGFA antibodies
This PDGFA antibody is un-conjugated
Application
All applications for PDGFA antibodies
Western Blotting (WB)
Sequence
HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTDVR
Predicted Reactivity
Dog: 85%, Guinea Pig: 82%, Human: 100%, Mouse: 85%, Rat: 85%
Characteristics
This is a rabbit polyclonal antibody against PDGFA. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDGFA
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Discover our top product PDGFA Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PDGFA
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Target
PDGFA
(Platelet Derived Growth Factor A (PDGFA))
Alternative Name
PDGFA (PDGFA Products )
Synonyms
PDGF-A antibody, PDGF1 antibody, pdgfa antibody, pdgfa-2 antibody, zgc:100777 antibody, pdgf antibody, pdgf1 antibody, pdgf-a antibody, AA409063 antibody, CD142 antibody, Cf-3 antibody, Cf3 antibody, TF antibody, PDGFACP antibody, wu:fc32c12 antibody, zgc:153249 antibody, platelet derived growth factor subunit A antibody, platelet-derived growth factor alpha polypeptide a antibody, coagulation factor III antibody, platelet derived growth factor, alpha antibody, platelet derived growth factor subunit A S homeolog antibody, platelet-derived growth factor alpha polypeptide b antibody, PDGFA antibody, pdgfaa antibody, pdgfa antibody, F3 antibody, Pdgfa antibody, pdgfa.S antibody, pdgfab antibody
Background
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. Alias Symbols: PDGF-A, PDGF1 Protein Interaction Partner: COL6A1, COL5A1, COL4A1, COL3A1, COL2A1, COL1A2, COL1A1, PDAP1, DUSP3, SPARC, PDGFRA, PDGFA, HSPG2, FURIN, A2M, PLCG1, Protein Size: 196
Molecular Weight
21 kDa
Gene ID
5154
NCBI Accession
NM_033023 , NP_148983
Pathways
RTK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Smooth Muscle Cell Migration , Platelet-derived growth Factor Receptor Signaling
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