DMRT1 antibody (N-Term)
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- Target See all DMRT1 Antibodies
- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Cow, Dog, Rabbit, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DMRT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PNDEAFSKPS TPSEAPHAPG VPPQGRAGGF GKASGALVGA ASGSSAGGSS
- Cross-Reactivity
- Cow (Bovine), Dog (Canine), Human, Pig (Porcine)
- Predicted Reactivity
- Cow: 78%, Dog: 85%, Human: 100%, Pig: 78%, Rabbit: 92%
- Characteristics
- This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMRT1
- Top Product
- Discover our top product DMRT1 Primary Antibody
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- Application Notes
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WB Suggested Anti-DMRT1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 373 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
- Alternative Name
- DMRT1 (DMRT1 Products)
- Synonyms
- DMT1 antibody, DMRT1 antibody, zgc:136676 antibody, dmrt1 antibody, dmrt1-alpha antibody, dmt1 antibody, dmrt1-beta antibody, xdmrt1 antibody, doublesex and mab-3 related transcription factor 1 antibody, doublesex and mab-3 related transcription factor 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 S homeolog antibody, DMRT1 antibody, Dmrt1 antibody, dmrt1 antibody, dmrt1.L antibody, dmrt1.S antibody
- Background
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The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DMT1
Protein Interaction Partner: Dlg4, TRIM29,
Protein Size: 373 - Molecular Weight
- 39 kDa
- Gene ID
- 1761
- NCBI Accession
- NM_021951, NP_068770
- UniProt
- Q9Y5R6
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