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PDZRN3 antibody (N-Term)
PDZRN3
Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDZRN3 Antibody
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Target
See all PDZRN3 Antibodies
PDZRN3
(PDZ Domain Containing Ring Finger 3 (PDZRN3))
Binding Specificity
All epitopes for PDZRN3 antibodies
N-Term
Reactivity
All reactivities for PDZRN3 antibodies
Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio)
Host
All hosts for PDZRN3 antibodies
Rabbit
Clonality
All clonalities for PDZRN3 antibodies
Polyclonal
Conjugate
All conjugates for PDZRN3 antibodies
This PDZRN3 antibody is un-conjugated
Application
All applications for PDZRN3 antibodies
Western Blotting (WB)
Sequence
ELDRFDGDVD PDLKCALCHK VLEDPLTTPC GHVFCAGCVL PWVVQEGSCP
Predicted Reactivity
Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 93%, Zebrafish: 79%
Characteristics
This is a rabbit polyclonal antibody against PDZRN3. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDZRN3
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PDZRN3
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Target
PDZRN3
(PDZ Domain Containing Ring Finger 3 (PDZRN3))
Alternative Name
PDZRN3 (PDZRN3 Products )
Synonyms
MGC80196 antibody, pdzrn3 antibody, LNX3 antibody, SEMACAP3 antibody, 1110020C07Rik antibody, AI429718 antibody, AL023082 antibody, Semcap3 antibody, PDZ domain containing ring finger 3 antibody, PDZ domain containing ring finger 3 L homeolog antibody, PDZ domain containing RING finger 3b antibody, E3 ubiquitin-protein ligase PDZRN3 antibody, PDZ domain containing RING finger 3 antibody, PDZRN3 antibody, pdzrn3.L antibody, pdzrn3b antibody, LOC100228989 antibody, pdzrn3 antibody, Pdzrn3 antibody
Background
PDZRN3 is a E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation. Protein Interaction Partner: Dlg4, LNX2, LNX1, UBE2D2, MUSK, PDZRN3, BMPR2, EFNB2, Protein Size: 729
Molecular Weight
80 kDa
Gene ID
23024
Pathways
Skeletal Muscle Fiber Development
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