GJA8 antibody (Middle Region)

Catalog No. ABIN2774860

Product Details anti-GJA8 Antibody

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEQEKVAVPE GEKVETPGVD KEGEKEEPQS EKVSKQGLPA EKTPSLCPEL

Predicted Reactivity: Dog: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GJA8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJA8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJA8

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Alternative Name: GJA8 (GJA8 Products)

Synonyms: Aey5 antibody, Cnx50 antibody, Cx50 antibody, Lop10 antibody, CAE antibody, CAE1 antibody, CTRCT1 antibody, CX50 antibody, CZP1 antibody, MP70 antibody, Cx45.6 antibody, gap junction protein, alpha 8 antibody, gap junction protein alpha 8 antibody, Gja8 antibody, GJA8 antibody

Background: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1).
Alias Symbols: CAE, CAE1, CX50, CZP1, MP70
Protein Interaction Partner: TJP1, MIP,
Protein Size: 433

Molecular Weight: 48 kDa

Gene ID: 2703

NCBI Accession: NM_005267, NP_005258

UniProt: P48165