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Fibrinogen beta Chain antibody (Middle Region)
FGB
Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Fibrinogen beta Chain Antibody
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Target
See all Fibrinogen beta Chain (FGB) Antibodies
Fibrinogen beta Chain (FGB)
Binding Specificity
All epitopes for Fibrinogen beta Chain antibodies
Middle Region
Reactivity
All reactivities for Fibrinogen beta Chain antibodies
Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Dog
Host
All hosts for Fibrinogen beta Chain antibodies
Rabbit
Clonality
All clonalities for Fibrinogen beta Chain antibodies
Polyclonal
Conjugate
All conjugates for Fibrinogen beta Chain antibodies
This Fibrinogen beta Chain antibody is un-conjugated
Application
All applications for Fibrinogen beta Chain antibodies
Western Blotting (WB)
Sequence
GNDKISQLTR MGPTELLIEM EDWKGDKVKA HYGGFTVQNE ANKYQISVNK
Predicted Reactivity
Cow: 91%, Dog: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
Characteristics
This is a rabbit polyclonal antibody against FGB. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FGB
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Fibrinogen beta Chain
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Target
Fibrinogen beta Chain (FGB)
Alternative Name
FGB (FGB Products )
Synonyms
FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Alias Symbols: HEL-S-78p Protein Size: 272
Molecular Weight
29 kDa
Gene ID
2244
NCBI Accession
NM_001184741 , NP_001171670
UniProt
P02675
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