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CREB3L2 antibody (N-Term)

CREB3L2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775946
  • Target See all CREB3L2 Antibodies
    CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
    Host
    • 29
    • 2
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CREB3L2 antibody is un-conjugated
    Application
    • 26
    • 22
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    HSYSLCEEPR AQSPFTHITS DSFNDDEVES EKWYLSTDF
    Predicted Reactivity
    Cow: 93%, Dog: 85%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 86%, Rabbit: 87%, Rat: 87%
    Characteristics
    This is a rabbit polyclonal antibody against CREB3L2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CREB3L2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 520 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lynch, Maillet, Vanhoutte, Schloemer, Sargent, Blair, Lynch, Okada, Aronow, Osinska, Prywes, Lorenz, Mori, Lawler, Robbins, Molkentin: "A thrombospondin-dependent pathway for a protective ER stress response." in: Cell, Vol. 149, Issue 6, pp. 1257-68, (2012) (PubMed).

    Fox, Hanlon, Andrew: "The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity." in: The Journal of cell biology, Vol. 191, Issue 3, pp. 479-92, (2010) (PubMed).

    Sievert, Jackson, Gai, Hakonarson, Judkins, Resnick, Sutton, Storm, Shaikh, Biegel: "Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene." in: Brain pathology (Zurich, Switzerland), Vol. 19, Issue 3, pp. 449-58, (2009) (PubMed).

    Storlazzi, Mertens, Nascimento, Isaksson, Wejde, Brosjo, Mandahl, Panagopoulos: "Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma." in: Human molecular genetics, Vol. 12, Issue 18, pp. 2349-58, (2003) (PubMed).

  • Target
    CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
    Alternative Name
    CREB3L2 (CREB3L2 Products)
    Synonyms
    CREB3L2 antibody, bbf2h7 antibody, BBF2H7 antibody, C530025K05Rik antibody, Ra69 antibody, SCIRR69 antibody, zgc:158603 antibody, cAMP responsive element binding protein 3 like 2 antibody, cAMP responsive element binding protein 3-like 2 antibody, cAMP responsive element binding protein 3-like 2 L homeolog antibody, CREB3L2 antibody, creb3l2 antibody, Creb3l2 antibody, creb3l2.L antibody
    Background
    CREB3L2 is a member of the old astrocyte specifically induced substance (OASIS) DNA binding and basic leucine zipper dimerization (bZIP) family of transcription factors, which includes CREB3 (MIM 606443) and CREB4 (MIM 607138).
    Alias Symbols: BBF2H7
    Protein Interaction Partner: Fbxw7, UBE2D3, UBA1, GAS7, UBC, GCFC2, RGS16, PXN, CEP19, GULP1, RND1, ZNF212, PTP4A1, ELAVL1, SUMO2, Dynll1,
    Protein Size: 520
    Molecular Weight
    57 kDa
    Gene ID
    64764
    NCBI Accession
    NM_194071, NP_919047
    UniProt
    Q70SY1
    Pathways
    Thyroid Hormone Synthesis
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