TCEB2 antibody (Middle Region)
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- Target See all TCEB2 Antibodies
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Goat, Zebrafish (Danio rerio), Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCEB2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- TARPQAPATV GLAFRADDTF EALCIEPFSS PPELPDVMKP QDSGSSANEQ
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against TCEB2. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TCEB2
- Top Product
- Discover our top product TCEB2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 118 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- Alternative Name
- TCEB2 (TCEB2 Products)
- Synonyms
- 0610040H15Rik antibody, cb162 antibody, wu:fb47e08 antibody, ELOB antibody, SIII antibody, elongin B antibody, Elob antibody, elob antibody, ELOB antibody
- Background
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TCEB2 is the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: SIII, ELOB
Protein Interaction Partner: vif, TCEB1, SOCS4, CUL5, UBC, PRAME, VHL, ASB18, ASB12, ASB14, ASB15, ASB9, ASB8, ASB7, ASB6, ASB5, ASB10, ASB17, ASB16, ASB13, ASB1, ASB3, LRRC47, LARS, EPRS, CDC42, CUL2, ASB2, Zswim8, CSNK1E, NOS2, NEDD8, HIF1A, CFTR, FEM1B, SOCS3, EPAS1, Lrrc41, Wsb1,
Protein Size: 118 - Molecular Weight
- 13 kDa
- Gene ID
- 6923
- NCBI Accession
- NM_007108, NP_009039
- UniProt
- Q15370
- Pathways
- SARS-CoV-2 Protein Interactome
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