MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibody

Details for Product No. ABIN2777403, Supplier: Log in to see
Antigen
  • evi1
  • im:7140716
  • prdm3
  • EVI1
  • AML1-EVI-1
  • MDS1
  • MDS1-EVI1
  • PRDM3
  • D630039M04Rik
  • Evi-1
  • Evi1
  • Jbo
  • Mds
  • Mds1
  • Mds1-Evi1
  • Prdm3
  • Znfpr1b1
  • AML1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • MDS1 and EVI1 complex locus
  • runt-related transcription factor 1
  • mecom
  • MECOM
  • LOC100343228
  • Mecom
  • RUNX1
Epitope
C-Term
29
17
17
15
9
5
5
4
4
3
3
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
105
33
8
3
3
2
2
1
1
1
1
Host
Rabbit
71
31
15
Clonality
Polyclonal
Conjugate
Un-conjugated
6
6
6
6
6
6
Application
Immunohistochemistry (IHC), Western Blotting (WB)
104
65
10
6
3
2
1
1
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human EVI1
Blocking Peptide Blocking peptide for this product available: ABIN976486
Sequence HFTDSLKMRK MEDNQYSEAE LSSFSTSHVP EELKQPLHRK SKSQAYAMML
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against EVI1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name EVI1 (MECOM Antibody Abstract)
Background EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
Alias Symbols: AML1-EVI-1, EVI-1, MDS1-EVI1, MGC163392, PRDM3, EVI1, MDS1
Protein Interaction Partner: PRMT1, PIAS4, SUMO1, SOX2, ELAVL1, SIRT1, KAT2B, SMAD4, SMAD3, SMAD2, SMAD1, EHMT2, SUV39H1, MECOM, HDAC1, HDAC4, CTBP2, CTBP1, CREBBP, MBD3,
Protein Size: 1051
Molecular Weight 118 kDa
Gene ID 2122
NCBI Accession NM_005241, NP_005232
UniProt Q03112
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1051 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibody (ABIN2777403) Host: Rabbit Target Name: EVI1 Sample Tissue: Human 293T Antibody Dilution: 1.0ug/ml
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibody (ABIN2777403) Host: Rabbit Target Name: MECOM Sample Tissue: Human 293T Whole Cell Antibody Dilutio...
Immunohistochemistry (IHC) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibody (ABIN2777403) Human Intestine
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibody (ABIN2777403) WB Suggested Anti-EVI1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive ...
Background publications Chi, Senyuk, Chakraborty, Nucifora: "EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity." in: The Journal of biological chemistry, Vol. 278, Issue 50, pp. 49806-11, 2003 (PubMed).