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MECOM antibody
MECOM
Reactivity: Human, Mouse
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Catalog No. ABIN7248587
$528.80
Plus shipping costs $45.00
20 μL ABIN7004860
60 μL ABIN7248585
120 μL ABIN7248586
200 μL ABIN7248587
20 μL ABIN7004860
60 μL ABIN7248585
120 μL ABIN7248586
200 μL ABIN7248587
Delivery in 8 to 11 Business Days
Product Details anti-MECOM Antibody
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Target
See all MECOM Antibodies
MECOM
(MDS1 and EVI1 Complex Locus (MECOM))
Reactivity
All reactivities for MECOM antibodies
Human, Mouse
Host
All hosts for MECOM antibodies
Rabbit
Clonality
All clonalities for MECOM antibodies
Polyclonal
Conjugate
All conjugates for MECOM antibodies
This MECOM antibody is un-conjugated
Application
All applications for MECOM antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Antigen affinity purification
Immunogen
Synthetic peptide of human MECOM
Isotype
IgG
Alternatives
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Application Details
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Application Notes
IHC 1:40-1:200, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.68 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MECOM
(hide)
Target
MECOM
(MDS1 and EVI1 Complex Locus (MECOM))
Alternative Name
MECOM (MECOM Products )
Synonyms
AML1-EVI-1 antibody, EVI1 antibody, MDS1 antibody, MDS1-EVI1 antibody, PRDM3 antibody, D630039M04Rik antibody, Evi-1 antibody, Evi1 antibody, Jbo antibody, Mds antibody, Mds1 antibody, Mds1-Evi1 antibody, Prdm3 antibody, Znfpr1b1 antibody, evi1 antibody, im:7140716 antibody, prdm3 antibody, evi-1 antibody, mecom antibody, mecom-a antibody, mecom-b antibody, xEvi-1 antibody, MDS1 and EVI1 complex locus antibody, MDS1 and EVI1 complex locus L homeolog antibody, MECOM antibody, Mecom antibody, mecom antibody, mecom.L antibody
Background
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
UniProt
Q03112