HES6 antibody (Middle Region)
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- Target See all HES6 Antibodies
- HES6 (Hairy and Enhancer of Split 6 (HES6))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HES6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LLAGTEVQAK LENAEVLELT VRRVQGALRG RAREREQLQA EASERFAAGY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against Hes6. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Hes6
- Top Product
- Discover our top product HES6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 224 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HES6 (Hairy and Enhancer of Split 6 (HES6))
- Alternative Name
- Hes6 (HES6 Products)
- Synonyms
- YF-30 antibody, her13.2 antibody, AI326893 antibody, bHLHb41 antibody, HES-6 antibody, bHLHc23 antibody, hes family bHLH transcription factor 6 antibody, hairy and enhancer of split 6 antibody, hes6 antibody, Hes6 antibody, HES6 antibody
- Background
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Hes6 does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Hes6 also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. It promotes cell differentiation.
Alias Symbols: AI326893, bHLHb41
Protein Interaction Partner: Tle1, Tef, Mycn, Ssbp3, Hes1,
Protein Size: 224 - Molecular Weight
- 24 kDa
- Gene ID
- 55927
- NCBI Accession
- NM_019479, NP_062352
- UniProt
- Q9JHE6
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