TAF2 antibody (Middle Region)

Catalog No. ABIN2777909

Product Details anti-TAF2 Antibody

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Horse, Rat, Rabbit, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF2 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: RKRNVLELEI KQDYTSPGTQ KYVGPLKVTV QELDGSFNHT LQIEENSLKH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against TAF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TAF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1199 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF2

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Alternative Name: TAF2 (TAF2 Products)

Synonyms: CG6711 antibody, Dmel\\CG6711 antibody, TAF antibody, TAF150 antibody, TAF2 antibody, TAFII150 antibody, TAF[II]150 antibody, TAF[[II]] antibody, TAF[[II]]150 antibody, TFIID antibody, Taf150 antibody, TafII150 antibody, Taf[[II]]150 antibody, dTAF II 150 antibody, dTAF150 antibody, dTAFII150 antibody, dTAF[[II]]150 antibody, TAFII-150 antibody, fc30f02 antibody, wu:fc30f02 antibody, 150kDa antibody, 4732460C16Rik antibody, AI425886 antibody, CIF150 antibody, TAF2B antibody, TAFIIB antibody, TBP-associated factor 2 antibody, TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor antibody, TATA-box binding protein associated factor 2 antibody, TATA-box binding protein associated factor 2 S homeolog antibody, Taf2 antibody, taf2 antibody, taf2.S antibody, TAF2 antibody

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF2 is one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CIF150, TAF2B, TAFII150
Protein Interaction Partner: SHFM1, SOX2, SIRT1, RNPS1, MED26, HIST3H3, TAF9, TAF6, TAF1, ISG15, ESR1, TAF10, ELAVL1, UBC, TAF8, TERF2, TERF1, TBP, KDM5B, TAF13, TAF12, TAF11, TAF5, TAF4, TAF7,
Protein Size: 1199

Molecular Weight: 137 kDa

Gene ID: 6873

NCBI Accession: NM_003184, NP_003175

UniProt: Q6P1X5