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SMARCB1 antibody (Middle Region)

SMARCB1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778302
  • Target See all SMARCB1 Antibodies
    SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
    Binding Specificity
    • 16
    • 11
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 90
    • 57
    • 26
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 80
    • 10
    Rabbit
    Clonality
    • 72
    • 18
    Polyclonal
    Conjugate
    • 47
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMARCB1 antibody is un-conjugated
    Application
    • 52
    • 34
    • 15
    • 15
    • 13
    • 13
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PLTFVPAIAS AIRQQIESYP TDSILEDQSD QRVIIKLNIH VGNISLVDQF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against SMARCB1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SMARCB1
    Top Product
    Discover our top product SMARCB1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 376 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target
    SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
    Alternative Name
    SMARCB1 (SMARCB1 Products)
    Synonyms
    SMARCB1 antibody, BAF47 antibody, INI1 antibody, MRD15 antibody, RDT antibody, RTPS1 antibody, SNF5 antibody, SNF5L1 antibody, Sfh1p antibody, Snr1 antibody, hSNFS antibody, AU020204 antibody, Baf47 antibody, Ini1 antibody, SNF5/INI1 antibody, Snf5 antibody, fc51b01 antibody, smarcb1 antibody, wu:fc51b01 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b antibody, SMARCB1 antibody, Smarcb1 antibody, smarcb1.S antibody, smarcb1b antibody
    Background
    The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
    Alias Symbols: RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144
    Protein Interaction Partner: UBC, SOX2, tat, EPAS1, TRA2A, NCSTN, SAP18, EIF4A3, ARID1A, DPF1, VTN, TOP2B, SON, SMARCE1, SMARCD3, SMARCD2, SMARCD1, SMARCC2, SMARCA4, SMARCA2, SMARCC1, ARID1B, HDAC2, APP, PHF10, UBD, COPS5, CUL3, TFAP4, CAND1, RB1CC1, UBB, CEBPB, UL114, UL44, CHFR, DP
    Protein Size: 376
    Molecular Weight
    41 kDa
    Gene ID
    6598
    NCBI Accession
    NM_001007468, NP_001007469
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