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PRMT7 antibody (C-Term)

PRMT7 Reactivity: Human, Mouse, Rat, Horse, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778660
  • Target See all PRMT7 Antibodies
    PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
    Binding Specificity
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse, Dog, Guinea Pig
    Host
    • 32
    • 4
    • 1
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRMT7 antibody is un-conjugated
    Application
    • 26
    • 13
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV
    Predicted Reactivity
    Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product PRMT7 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 692 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
    Alternative Name
    Prmt7 (PRMT7 Products)
    Synonyms
    ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 7 antibody, ATPRMT7 antibody, DL4310W antibody, FCAALL.195 antibody, protein arginine methyltransferase 7 antibody, RGD1304869 antibody, 4933402B05Rik antibody, BC006705 antibody, zgc:66172 antibody, protein arginine methyltransferase 7 antibody, protein arginine methyltransferase 7 L homeolog antibody, protein arginine N-methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody, PRMT7 antibody, Prmt7 antibody, prmt7.L antibody, prmt7 antibody, prmt-7 antibody
    Background
    Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
    Alias Symbols: 4933402B05Rik, BC006705, MGC7929
    Protein Interaction Partner: Ctcfl,
    Protein Size: 692
    Molecular Weight
    78 kDa
    Gene ID
    214572
    NCBI Accession
    NM_145404, NP_663379
    UniProt
    Q922X9
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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