PRMT7 antibody (C-Term)
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- Target See all PRMT7 Antibodies
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Horse, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRMT7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV
- Predicted Reactivity
- Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PRMT7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 692 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
- Alternative Name
- Prmt7 (PRMT7 Products)
- Synonyms
- ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 7 antibody, ATPRMT7 antibody, DL4310W antibody, FCAALL.195 antibody, protein arginine methyltransferase 7 antibody, RGD1304869 antibody, 4933402B05Rik antibody, BC006705 antibody, zgc:66172 antibody, protein arginine methyltransferase 7 antibody, protein arginine methyltransferase 7 L homeolog antibody, protein arginine N-methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody, PRMT7 antibody, Prmt7 antibody, prmt7.L antibody, prmt7 antibody, prmt-7 antibody
- Background
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Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Alias Symbols: 4933402B05Rik, BC006705, MGC7929
Protein Interaction Partner: Ctcfl,
Protein Size: 692 - Molecular Weight
- 78 kDa
- Gene ID
- 214572
- NCBI Accession
- NM_145404, NP_663379
- UniProt
- Q922X9
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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