SRGN antibody (N-Term)
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- Target See all SRGN Antibodies
- SRGN (serglycin (SRGN))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rabbit, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SRGN antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LLKCSRLVLA LALILVLESS VQGYPTRRAR YQWVRCNPDS NSANCLEEKG
- Predicted Reactivity
- Human: 100%, Mouse: 91%, Rabbit: 85%, Rat: 91%
- Characteristics
- This is a rabbit polyclonal antibody against SRGN. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product SRGN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 158 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SRGN (serglycin (SRGN))
- Alternative Name
- SRGN (SRGN Products)
- Synonyms
- PPG antibody, PRG antibody, PRG1 antibody, Prg antibody, Prg1 antibody, Sgc antibody, Pgsg antibody, serglycin antibody, SRGN antibody, Srgn antibody
- Background
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SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.
Alias Symbols: FLJ12930, MGC9289, PPG, PRG, PRG1
Protein Interaction Partner: UBQLN1, SGTA, UBQLN4, PSRC1, CEP70, UBR4, BAG6, CCL3, PF4, GZMB, CD44, ALB,
Protein Size: 158 - Molecular Weight
- 15 kDa
- Gene ID
- 5552
- NCBI Accession
- NM_002727, NP_002718
- UniProt
- P10124
- Pathways
- Maintenance of Protein Location
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