NPAS4 antibody (Middle Region)

Catalog No. ABIN2779719

Product Details anti-NPAS4 Antibody

Target: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Pig, Sheep, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPAS4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QAHLDSPSQT FPEQLSPNPT KTYFAQEGCS FLYEKLPPSP SSPGNGDCTL

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against NPAS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPAS4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NPAS4 antibody (ABIN2779719)

Pruunsild, Sepp, Orav, Koppel, Timmusk: "Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 9, pp. 3295-308, (2011) (PubMed).

Target Details for NPAS4

Target: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Alternative Name: NPAS4 (NPAS4 Products)

Synonyms: LE-PAS antibody, Nxf antibody, Le-PAS antibody, NXF antibody, PASD10 antibody, bHLHe79 antibody, npas4 antibody, wu:fj52d04 antibody, zgc:136764 antibody, MGC146621 antibody, neuronal PAS domain protein 4 antibody, neuronal PAS domain protein 4a antibody, neuronal PAS domain-containing protein 4 antibody, Npas4 antibody, NPAS4 antibody, npas4a antibody, npas4 antibody, Tsp_02837 antibody

Background: NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2, MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events.NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2, MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM].
Alias Symbols: Le-PAS, NXF, PASD10, bHLHe79
Protein Interaction Partner: ARNT2, ARNTL, ARNT,
Protein Size: 802

Molecular Weight: 87 kDa

Gene ID: 266743

NCBI Accession: NM_178864, NP_849195

UniProt: Q8IUM7