TFAM antibody (Middle Region)
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- Target See all TFAM Antibodies
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Binding Specificity
- Middle Region
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Reactivity
- Mouse, Rat, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TFAM antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SESFQEAKDD SAQGKLKLVN EAWKNLSPEE KQAYIQLAKD DRIRYDNEMK
- Predicted Reactivity
- Mouse: 100%, Rabbit: 77%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against TFAM. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM
- Top Product
- Discover our top product TFAM Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 243 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Alternative Name
- TFAM (TFAM Products)
- Synonyms
- tcf6 antibody, mttf1 antibody, mttfa antibody, tcf6l1 antibody, tcf6l2 antibody, tcf6l3 antibody, mttfa-A antibody, xl-mtTFA antibody, MGC153358 antibody, zgc:153358 antibody, MTTF1 antibody, MTTFA antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, AI661103 antibody, Hmgts antibody, mtTFA antibody, tsHMG antibody, Mttfa antibody, transcription factor A, mitochondrial antibody, transcription factor A, mitochondrial L homeolog antibody, TFAM antibody, tfam.L antibody, tfam antibody, Tfam antibody
- Background
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Interaction Partner: C1QBP, SNCA,
Protein Size: 243 - Molecular Weight
- 27 kDa
- Gene ID
- 21780
- NCBI Accession
- NM_009360, NP_033386
- UniProt
- P40630
- Pathways
- Chromatin Binding
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