IRF5 antibody (N-Term)
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- Target See all IRF5 Antibodies
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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Binding Specificity
- N-Term
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP
- Predicted Reactivity
- Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
- Top Product
- Discover our top product IRF5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 497 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." in: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).
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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." in: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).
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- Target
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Alternative Name
- IRF5 (IRF5 Products)
- Synonyms
- IRF5 antibody, irf5 antibody, SLEB10 antibody, AW491843 antibody, mirf5 antibody, im:7155364 antibody, zgc:76986 antibody, interferon regulatory factor 5 antibody, interferon regulatory factor 5 L homeolog antibody, IRF5 antibody, irf5 antibody, Irf5 antibody, irf5.L antibody
- Background
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The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
Alias Symbols: mirf5, AW491843
Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
Protein Size: 497 - Molecular Weight
- 55 kDa
- Gene ID
- 27056
- NCBI Accession
- NM_012057, NP_036187
- UniProt
- P56477
- Pathways
- TLR Signaling, Autophagy
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