Fibrillin 1 antibody (N-Term)
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- Target See all Fibrillin 1 (FBN1) Antibodies
- Fibrillin 1 (FBN1)
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Fibrillin 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MRRGRLLEIA LGFTVLLASY TSHGADANLE AGNVKETRAS RAKRRGGGGH
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 100%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against FBN1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FBN1
- Top Product
- Discover our top product FBN1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 195 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Fibrillin 1 (FBN1)
- Alternative Name
- FBN1 (FBN1 Products)
- Synonyms
- FBN1 antibody, ACMICD antibody, ECTOL1 antibody, FBN antibody, GPHYSD2 antibody, MASS antibody, MFS1 antibody, OCTD antibody, SGS antibody, SSKS antibody, WMS antibody, WMS2 antibody, AI536462 antibody, B430209H23 antibody, Fib-1 antibody, Tsk antibody, fibrillin 1 antibody, FBN1 antibody, Fbn1 antibody
- Background
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FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.
Alias Symbols: FBN, SGS, WMS, MASS, MFS1, OCTD, SSKS, WMS2, ACMICD, GPHYSD2
Protein Interaction Partner: UBC, SPRY2, ATXN7, MYOC, MFAP5, MFAP2, LTBP1, HSPG2, FBLN2, ELN, DCN, FBN2, VCAN, CALR,
Protein Size: 195 - Molecular Weight
- 21 kDa
- Gene ID
- 2200
- NCBI Accession
- NM_000138
- UniProt
- Q75N89
- Pathways
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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