IRF5 antibody (N-Term)
-
- Target See all IRF5 Antibodies
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This IRF5 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- PTPPRRVRLK PWLVAQVNSC QYPGLQWVNG EKKLFCIPWR HATRHGPSQD
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
- Characteristics
- This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human IRF5
- Top Product
- Discover our top product IRF5 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 498 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Alternative Name
- IRF5 (IRF5 Products)
- Synonyms
- IRF5 antibody, irf5 antibody, SLEB10 antibody, AW491843 antibody, mirf5 antibody, im:7155364 antibody, zgc:76986 antibody, interferon regulatory factor 5 antibody, interferon regulatory factor 5 L homeolog antibody, IRF5 antibody, irf5 antibody, Irf5 antibody, irf5.L antibody
- Background
-
IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
Alias Symbols: SLEB10
Protein Interaction Partner: SGTA, IRF5, COPS7B, COPS4, COPS5, COPS6, COPS8, COPS2, COPS3, UBC, GPS1, TRAF6, MYD88, RGS3, PPM1G, IRF6, HIVEP1, GRB2, CHUK, ALPI, MAVS, GTPBP2, CEP152, GTPBP1, SIN3A, NCOR2, NCOR1, KAT2B, HDAC1, EP300, CREBBP, TRIM15, IKBKE, TBK1, IRF3, XPO1,
Protein Size: 498 - Molecular Weight
- 56 kDa
- Gene ID
- 3663
- NCBI Accession
- NM_032643, NP_116032
- UniProt
- Q13568
- Pathways
- TLR Signaling, Autophagy
-