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PBX2 antibody (C-Term)

PBX2 Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780441
  • Target See all PBX2 Antibodies
    PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 43
    • 15
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio)
    Host
    • 38
    • 6
    Rabbit
    Clonality
    • 39
    • 5
    Polyclonal
    Conjugate
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PBX2 antibody is un-conjugated
    Application
    • 41
    • 21
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PGGYGDNLGG GQMYSPREMR ANGSWQEAVT PSSVTSPTEG PGSVHSDTSN
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PBX2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PBX2
    Top Product
    Discover our top product PBX2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 430 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))
    Alternative Name
    PBX2 (PBX2 Products)
    Synonyms
    G17 antibody, HOX12 antibody, PBX2MHC antibody, AU043397 antibody, pbxy antibody, wu:fb73g03 antibody, hox12 antibody, pbx2mhc antibody, PBX2P1 antibody, PBX homeobox 2 antibody, pre B cell leukemia homeobox 2 antibody, pre-B-cell leukemia homeobox 2 antibody, pre-B-cell leukemia homeobox 2 L homeolog antibody, PBX2 antibody, Pbx2 antibody, pbx2 antibody, pbx2.L antibody
    Background
    PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
    Alias Symbols: G17, HOX12, PBX2MHC
    Protein Interaction Partner: CARD9, HOXA1, SOX2, ELAVL1, COPS6, ZDHHC7, SKIV2L2, SMYD3, MCRS1, CCDC88B, RPS6KC1, PBX2, PBX1, CENPBD1, DCTN3, NUP62, BAIAP2, IKBKAP, UBE2E1, PKNOX1, BLOC1S1, RPL4, HOXB8, HOXA9,
    Protein Size: 430
    Molecular Weight
    46 kDa
    Gene ID
    5089
    NCBI Accession
    NM_002586, NP_002577
    UniProt
    P40425
    Pathways
    Skeletal Muscle Fiber Development
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