CCL17 antibody (N-Term)
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- Target See all CCL17 Antibodies
- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCL17 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FIIKLIKWLM IAIPATFVNS AIRYLECKLA LAFRTRLVDH AYETYFTNQT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against ABCD2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ABCD2
- Top Product
- Discover our top product CCL17 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 740 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
- Alternative Name
- ABCD2 (CCL17 Products)
- Synonyms
- A-152E5.3 antibody, ABCD-2 antibody, SCYA17 antibody, TARC antibody, CCL17 antibody, Abcd-2 antibody, Scya17 antibody, Scya17l antibody, Tarc antibody, abcd2 antibody, C-C motif chemokine ligand 17 antibody, chemokine (C-C motif) ligand 17 antibody, ATP-binding cassette sub-family D member 2 antibody, CCL17 antibody, Ccl17 antibody, LOC100537809 antibody
- Background
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
Alias Symbols: ABC39, ALDL1, ALDR, ALDRP, hALDR
Protein Interaction Partner: UBC, PXA1, PXA2, ABCD2, PEX19, ABCD1, ABCD3,
Protein Size: 740 - Molecular Weight
- 83 kDa
- Gene ID
- 225
- NCBI Accession
- NM_005164, NP_005155
- UniProt
- Q9UBJ2
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