SLC6A3 antibody (N-Term)

Catalog No. ABIN2781561

Product Details anti-SLC6A3 Antibody

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HCNNSWNSPN CSDAHPGDSS GDSSGLNDTF GTTPAAEYFE RGVLHLHQSH

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SLC6A3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC6A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 620 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC6A3

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Alternative Name: SLC6A3 (SLC6A3 Products)

Synonyms: DAT antibody, SLC6A3 antibody, Dat1 antibody, DAT1 antibody, PKDYS antibody, solute carrier family 6 member 3 antibody, solute carrier family 6 (neurotransmitter transporter), member 3 antibody, Sodium-dependent dopamine transporter antibody, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antibody, SLC6A3 antibody, slc6a3 antibody, dat-1 antibody, Slc6a3 antibody

Background: This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
Alias Symbols: DAT, DAT1
Protein Interaction Partner: SNTA1, TUBB1, TUBA1B, SNCA, CAMK2A, STX1A, NEDD4, UBC, PARK2, EPS15, EPN1, PICK1, TGFB1I1, GNB2L1, SLC6A3, DRD2,
Protein Size: 620

Molecular Weight: 68 kDa

Gene ID: 6531

NCBI Accession: NM_001044, NP_001035

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis