Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LCLAT1 antibody (Middle Region)

LCLAT1 Reactivity: Mouse, Human, Rat, Rabbit, Horse, Cow, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781857
  • Target See all LCLAT1 Antibodies
    LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
    Binding Specificity
    • 15
    • 9
    • 9
    • 6
    Middle Region
    Reactivity
    Mouse, Human, Rat, Rabbit, Horse, Cow, Dog, Guinea Pig
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LCLAT1 antibody is un-conjugated
    Application
    • 31
    • 15
    • 13
    • 13
    • 12
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE
    Predicted Reactivity
    Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human LYCAT
    Top Product
    Discover our top product LCLAT1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 376 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

  • Target
    LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
    Alternative Name
    LYCAT (LCLAT1 Products)
    Synonyms
    lclat1 antibody, zgc:77380 antibody, wu:fj17g04 antibody, LYCAT antibody, lycat antibody, agpat8 antibody, alcat1 antibody, 1agpat8 antibody, AGPATP8 antibody, 1AGPAT8 antibody, AGPAT8 antibody, ALCAT1 antibody, HSRG1849 antibody, UNQ1849 antibody, AI181996 antibody, Agpat8 antibody, Alcat1 antibody, Gm91 antibody, Lycat antibody, RGD1565906 antibody, lysocardiolipin acyltransferase 1 antibody, lclat1 antibody, LCLAT1 antibody, Lclat1 antibody
    Background
    LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
    Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
    Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
    Protein Size: 376
    Molecular Weight
    44 kDa
    Gene ID
    253558
    NCBI Accession
    NM_001002257, NP_001002257
    UniProt
    Q6UWP7
You are here:
Support