B4GALT2 antibody (Middle Region)
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- Target See all B4GALT2 Antibodies
- B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This B4GALT2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RLLIEFTSPM PLERVQRENP GVLMGGRYTP PDCTPAQTVA VIIPFRHREH
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 77%, Zebrafish: 77%
- Characteristics
- This is a rabbit polyclonal antibody against B4GALT2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human B4GALT2
- Top Product
- Discover our top product B4GALT2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))
- Alternative Name
- B4GALT2 (B4GALT2 Products)
- Synonyms
- B4Gal-T2 antibody, B4Gal-T3 antibody, beta4Gal-T2 antibody, Ggtb2 antibody, b4gal-t1 antibody, b4galt2 antibody, beta4gal-t1 antibody, cdg2d antibody, ggtb2 antibody, gt1 antibody, gtb antibody, b4gal-t2 antibody, beta4gal-t2 antibody, b4Gal-T2 antibody, si:ch211-261p7.4 antibody, CKII antibody, beta-1,4-galactosyltransferase 2 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 2 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 S homeolog antibody, B4GALT2 antibody, B4galt2 antibody, b4galt1.2 antibody, b4galt2.S antibody, b4galt2 antibody
- Background
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This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: B4Gal-T2, B4Gal-T3, beta4Gal-T2
Protein Interaction Partner: PFDN6,
Protein Size: 372 - Molecular Weight
- 42 kDa
- Gene ID
- 8704
- NCBI Accession
- NM_001005417, NP_001005417
- UniProt
- O60909
- Pathways
- Glycosaminoglycan Metabolic Process
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