COL6A1 antibody (Middle Region)
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- Target See all COL6A1 Antibodies
- COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COL6A1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ADITILLDGS ASVGSHNFDT TKRFAKRLAE RFLTAGRTDP AHDVRVAVVQ
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against COL6A1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human COL6A1
- Top Product
- Discover our top product COL6A1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1028 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))
- Alternative Name
- COL6A1 (COL6A1 Products)
- Synonyms
- CBR antibody, SDR21C1 antibody, hCBR1 antibody, OPLL antibody, AI747156 antibody, Col6a-1 antibody, RGD1565398 antibody, COL6A1 antibody, carbonyl reductase 1 antibody, collagen type VI alpha 1 chain antibody, collagen, type VI, alpha 1 antibody, collagen, type VI, alpha 1 L homeolog antibody, collagen type VI alpha 3 chain antibody, collagen alpha-1(VI) chain antibody, CBR1 antibody, COL6A1 antibody, Col6a1 antibody, col6a1.L antibody, COL6A3 antibody, col6a1 antibody, LOC100623720 antibody
- Background
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COL6A1 is a collagen VI which acts as a cell-binding protein.Defects in COL6A1 are a cause of Bethlem myopathy (BM).The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. This gene, which encodes a neural small non-messenger RNA, is a member of the family of interspersed repetitive DNA, and its product represents an example of a primate tissue-specific RNA polymerase III transcript. The RNA sequence is divided into three domains: a 5' portion homologous to the Alu Lm, a central adenosine-rich region, and the terminal 43-nt nonrepetitive domain. It is believed that this gene was retropositionally generated and recruited into a function regulating dendritic protein biosynthesis. At least two pseudogenes of this gene have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-200 AF020057.2 4262-4461
Alias Symbols: OPLL
Protein Interaction Partner: PDGFB, PDGFA, PDIA3, FBXO6, UBC, VHL, DNAJB11, LGALS3BP, LAMB1, FGF7, COL2A1, MAG, DCN,
Protein Size: 1028 - Molecular Weight
- 106 kDa
- Gene ID
- 1291
- NCBI Accession
- NM_001848, NP_001839
- UniProt
- P12109
- Pathways
- Growth Factor Binding, SARS-CoV-2 Protein Interactome
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