APEH antibody (Middle Region)
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- Target See all APEH Antibodies
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Cow, Horse, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APEH antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GSTGFGQDSI LSLPGNVGHQ DVKDVQFAVE QVLQEEHFDA SHVALMGGSH
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against APEH. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human APEH
- Top Product
- Discover our top product APEH Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 732 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
- Alternative Name
- APEH (APEH Products)
- Synonyms
- AARE antibody, ACPH antibody, APH antibody, D3F15S2 antibody, D3S48E antibody, DNF15S2 antibody, OPH antibody, AAP antibody, cb5 antibody, sb:cb5 antibody, wu:fi37d02 antibody, acylaminoacyl-peptide hydrolase antibody, acylpeptide hydrolase antibody, APEH antibody, Apeh antibody, apeh antibody
- Background
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APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Alias Symbols: ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE
Protein Interaction Partner: IST1, UBC, LGALS8, APEH, SNX6, CAND1, TOLLIP, CYHR1, JMJD6, HSPA4L, IPO7, DNM1L, VPS26A, NMI, H1FX, ZYX, TBCD, TARS, STAT1, SHMT2, SHMT1, PPM1G, SERPINE2, PAWR, LAMP2, KARS, HIST1H1C, GARS, CTTN, CARS, PREPL, SHBG, UBA5, TMEM62,
Protein Size: 732 - Molecular Weight
- 81 kDa
- Gene ID
- 327
- NCBI Accession
- NM_001640, NP_001631
- UniProt
- P13798
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