SHMT1 antibody (N-Term)
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- Target See all SHMT1 Antibodies
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Zebrafish (Danio rerio), Sheep, Rabbit, Cow, Horse, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SHMT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NIIKKESNRQ RVGLELIASE NFASRAVLEA LGSCLNNKYS EGYPGQRYYG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SHMT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SHMT1
- Top Product
- Discover our top product SHMT1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 483 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- Alternative Name
- SHMT1 (SHMT1 Products)
- Synonyms
- Shmt antibody, mShmt antibody, LRRGT00032 antibody, shmt1 antibody, MGC53442 antibody, zgc:66171 antibody, zgc:77524 antibody, SHMT1 antibody, Shmt1 antibody, CSHMT antibody, SHMT antibody, AI324848 antibody, AI385541 antibody, C81125 antibody, mshmt antibody, mshmt1 antibody, mshmt2 antibody, MEL-32 antibody, SHMT2 antibody, F20D10.50 antibody, F20D10_50 antibody, SERINE HYDROXYMETHYLTRANSFERASE 1 antibody, SERINE TRANSHYDROXYMETHYLASE antibody, SERINE TRANSHYDROXYMETHYLTRANSFERASE antibody, STM antibody, serine transhydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 (soluble) L homeolog antibody, serine hydroxymethyltransferase 1 (soluble) antibody, microRNA 6778 antibody, serine transhydroxymethyltransferase 1 antibody, Shmt1 antibody, shmt1.L antibody, shmt1 antibody, MIR6778 antibody, SHMT1 antibody, SHM1 antibody
- Background
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This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: CSHMT, MGC15229, MGC24556, SHMT
Protein Interaction Partner: UBC, SULT1A3, SHMT1, MAPK9, C18orf25, FAM129B, SNX6, XPO5, VPS29, PBDC1, GSPT2, HIST1H4A, CARS, ATP6V1C1, APEH, CTTN, TTC1, TSN, STAT1, SNX2, SHMT2, PAWR, IDE, HARS, GTF2F2, GARS, DEDD, MCAT, ZC3H4, HSPA1L, SUMO1, SUMO2, SUMO3, PRSS23, PIM1, CSNK2B, DLEU1
Protein Size: 483 - Molecular Weight
- 53 kDa
- Gene ID
- 6470
- NCBI Accession
- NM_004169, NP_004160
- UniProt
- Q5RFK5
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