ALG1 antibody (N-Term)
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- Target See all ALG1 Antibodies
- ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ALG1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VVLGDVGRSP RMQYHALSLA MHGFSVTLLG FCNSKPHDEL LQNNRIQIVG
- Predicted Reactivity
- Cow: 79%, Human: 100%, Mouse: 85%, Rabbit: 79%, Rat: 79%, Yeast: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ALG1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALG1
- Top Product
- Discover our top product ALG1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 464 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))
- Alternative Name
- ALG1 (ALG1 Products)
- Synonyms
- CDG1K antibody, HMAT1 antibody, HMT-1 antibody, HMT1 antibody, MT-1 antibody, Mat-1 antibody, hMat-1 antibody, zgc:66221 antibody, wu:fi34b12 antibody, alg1 antibody, hmat1 antibody, hmt1 antibody, ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase antibody, asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase) antibody, Beta-mannosyltransferase antibody, ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase L homeolog antibody, ALG1 antibody, Alg1 antibody, alg1 antibody, alg1.L antibody
- Background
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ALG1 catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K).The biosynthesis of lipid-linked oligosaccharides is highly conserved among eukaryotes and is catalyzed by 14 glycosyltransferases in an ordered stepwise manner. Mannosyltransferase I (MT I) catalyzes the first mannosylation step in this process.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-421 BM767933.1 1-421 422-1179 AY359073.1 416-1173 1180-1444 CA455103.1 259-523 1445-1939 CD366777.1 17-511 c 1940-2122 BC031095.1 1931-2113 2123-2149 BQ002699.1 1-27 c
Alias Symbols: HMAT1, HMT-1, HMT1, MT-1, CDG1K, Mat-1, hMat-1
Protein Interaction Partner: UBC, FBXO6, BAG3, MMS19,
Protein Size: 464 - Molecular Weight
- 52 kDa
- Gene ID
- 56052
- NCBI Accession
- NM_019109, NP_061982
- UniProt
- Q9BT22
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