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NTRK3 antibody (C-Term)

NTRK3 Reactivity: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784511
  • Target See all NTRK3 Antibodies
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    Binding Specificity
    • 19
    • 11
    • 9
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 70
    • 41
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig
    Host
    • 74
    • 8
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 80
    • 8
    Polyclonal
    Conjugate
    • 53
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NTRK3 antibody is un-conjugated
    Application
    • 68
    • 49
    • 37
    • 9
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ERPRVCPKEV YDVMLGCWQR EPQQRLNIKE IYKILHALGK ATPIYLDILG
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against NTRK3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK3
    Top Product
    Discover our top product NTRK3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 825 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    Alternative Name
    NTRK3 (NTRK3 Products)
    Synonyms
    TRKC antibody, gp145(trkC) antibody, trkC antibody, AW125844 antibody, Ntrk3_tv3 antibody, TrkC antibody, neurotrophic receptor tyrosine kinase 3 antibody, neurotrophic tyrosine kinase, receptor, type 3 antibody, NTRK3 antibody, Ntrk3 antibody
    Background
    NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
    Alias Symbols: TRKC, gp145(trkC)
    Protein Interaction Partner: TNK2, IRAK3, HSP90AA1, APP, SHC2, KIDINS220, DOK5, RASGRF1, MAPK3, DYNLL1, SQSTM1, SHC1, NGFRAP1, IRAK1, HTR2A, MAPK1, PTPN1, PLCG1, JUN, NTF3, NGFR, FRS2,
    Protein Size: 825
    Molecular Weight
    89 kDa
    Gene ID
    4916
    NCBI Accession
    NM_002530, NP_002521
    Pathways
    RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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