CELA1 antibody (N-Term)

Catalog No. ABIN2784732

Product Details anti-CELA1 Antibody

Target: CELA1 (Chymotrypsin-Like Elastase Family, Member 1 (CELA1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVLYGHSTQD LPETNARVVG GTEAGRNSWP SQISLQYRSG GSRYHTCGGT

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 77%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ELA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ELA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 258 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CELA1

Target: CELA1 (Chymotrypsin-Like Elastase Family, Member 1 (CELA1))

Alternative Name: ELA1 (CELA1 Products)

Synonyms: ELA1 antibody, 1810009A17Rik antibody, 1810062B19Rik antibody, Ela-1 antibody, Ela1 antibody, PC-TsF antibody, ela1 antibody, ELS1 antibody, Elastase-1 antibody, ELAI1 antibody, RATELAI1 antibody, chymotrypsin like elastase family member 1 antibody, chymotrypsin-like elastase family, member 1 antibody, CELA1 antibody, Cela1 antibody, cela1 antibody

Background: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 (ELA1) expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-867 BC069454.1 1-867 868-952 AF120493.1 868-952
Alias Symbols: ELA1
Protein Interaction Partner: PI3, SERPINA1, LPA,
Protein Size: 258

Molecular Weight: 28 kDa

Gene ID: 1990

NCBI Accession: NM_001971, NP_001962

UniProt: Q9UNI1