MVK antibody (N-Term)
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- Target See all MVK Antibodies
- MVK (Mevalonate Kinase (MVK))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MVK antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- LAVLAFLYLY LSICRKQRAL PSLDIVVWSE LPPGAGLGSS AAYSVCLAAA
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against MVK. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MVK
- Top Product
- Discover our top product MVK Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 396 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MVK (Mevalonate Kinase (MVK))
- Alternative Name
- MVK (MVK Products)
- Synonyms
- F21A20.160 antibody, F21A20_160 antibody, MEVALONATE KINASE antibody, MVK antibody, mevalonate kinase antibody, DDBDRAFT_0168621 antibody, DDBDRAFT_0302479 antibody, DDB_0168621 antibody, DDB_0302479 antibody, LRBP antibody, MK antibody, MVLK antibody, POROK3 antibody, 2310010A05Rik antibody, AI256848 antibody, AI414037 antibody, zgc:103473 antibody, mevalonate kinase antibody, mvk antibody, hypothetical protein antibody, MVK antibody, MK antibody, MA_RS03165 antibody, PAB_RS02890 antibody, LMOf2365_0011 antibody, mvk antibody, RCI_RS14145 antibody, TGAM_RS08735 antibody, MMAH_RS07705 antibody, TAGG_RS01605 antibody, SHELL_RS02965 antibody, MVOL_RS03085 antibody, Igag_1464 antibody, VDIS_RS11260 antibody, MFER_RS04560 antibody, DESMU_RS01555 antibody, ARCVE_RS02955 antibody, MZHIL_RS05110 antibody, Mvk antibody
- Background
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MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
Alias Symbols: LRBP, MVLK, MK
Protein Interaction Partner: MVK, PPP1CB, GSS, MAT1A, POT1, TERF1, UBC, EWSR1,
Protein Size: 396 - Molecular Weight
- 42 kDa
- Gene ID
- 4598
- NCBI Accession
- NM_000431, NP_000422
- UniProt
- Q03426
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