Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MVK Products

(Mevalonate Kinase (MVK))

Categories

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured MVK Categories

MVK Antibodies

High quality antibodies with extensive validation data.

MVK ELISA Kits

Reliable ELISA kits for a wide range of species.

MVK Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MVK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257334
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7237444
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN518109
Quantity 100 μg
Datasheet Datasheet

Recommended MVK ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968601
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648084
Quantity 96 tests
Datasheet Datasheet

Recommended MVK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7197016
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119830
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3082563
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MVK products

Celsi, Piscianz, Romano, Crovella: "Knockdown of MVK does not lead to changes in NALP3 expression or activation." in: Journal of inflammation (London, England), Vol. 12, pp. 7, (2015) (PubMed).

Calvisi, Wang, Ho, Ladu, Lee, Mattu, Destefanis, Delogu, Zimmermann, Ericsson, Brozzetti, Staniscia, Chen, Dombrowski, Evert: "Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma." in: Gastroenterology, Vol. 140, Issue 3, pp. 1071-83, (2011) (PubMed).

Nair, Menon: "Isolation and characterization of a novel trans-factor for luteinizing hormone receptor mRNA from ovary." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 14937-44, (2004) (PubMed).

Simon, Kremer, Wevers, Scheffer, De Jong, Van Der Meer, Drenth: "Mevalonate kinase deficiency: Evidence for a phenotypic continuum." in: Neurology, Vol. 62, Issue 6, pp. 994-7, (2004) (PubMed).

Stojanov, Lohse, Lohse, Hoffmann, Renner, Zellerer, Kéry, Shin, Haas, Hoffmann, Belohradsky et al.: "Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a ..." in: Arthritis and rheumatism, Vol. 50, Issue 6, pp. 1951-8, (2004) (PubMed).

Synonyms and alternative names related to MVK

mevalonate kinase (MVK), mevalonate kinase (MK), mevalonate kinase (MA_RS03165), mevalonate kinase (PAB_RS02890), mevalonate kinase (LMOf2365_0011), mvk (mvk), mevalonate kinase (mvk), mevalonate kinase (RCI_RS14145), mevalonate kinase (TGAM_RS08735), mevalonate kinase (MMAH_RS07705), hypothetical protein (TAGG_RS01605), mevalonate kinase (SHELL_RS02965), mevalonate kinase (MVOL_RS03085), mevalonate kinase (Igag_1464), mevalonate kinase (VDIS_RS11260), mevalonate kinase (MFER_RS04560), mevalonate kinase (DESMU_RS01555), mevalonate kinase (ARCVE_RS02955), mevalonate kinase (MZHIL_RS05110), mevalonate kinase (Mvk), 2310010A05Rik, AI256848, AI414037, DDBDRAFT_0168621, DDBDRAFT_0302479, DDB_0168621, DDB_0302479, F21A20.160, F21A20_160, LRBP, MEVALONATE KINASE, mevalonate kinase, MK, MVK, MVLK, POROK3, zgc:103473

Protein level used designations for MVK

  • mevalonate kinase
  • LH receptor mRNA-binding protein
  • mevalonate kinase 1
  • MK
  • mevalonate kinase (mevalonic aciduria)
You are here:
Support