RPA1 antibody (Middle Region)
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- Target See all RPA1 Antibodies
- RPA1 (Replication Protein A1, 70kDa (RPA1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Sheep, Cow, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RPA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TLWGEDADKF DGSRQPVLAI KGARVSDFGG RSLSVLSSST IIANPDIPEA
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%
- Characteristics
- This is a rabbit polyclonal antibody against RPA1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RPA1
- Top Product
- Discover our top product RPA1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 616 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RPA1 (Replication Protein A1, 70kDa (RPA1))
- Alternative Name
- RPA1 (RPA1 Products)
- Synonyms
- HSSB antibody, MST075 antibody, REPA1 antibody, RF-A antibody, RP-A antibody, RPA70 antibody, Cb1-727 antibody, wu:fi14b08 antibody, zgc:55337 antibody, zgc:77092 antibody, RPA1 antibody, hssb antibody, mst075 antibody, repa1 antibody, rf-a antibody, rp-a antibody, rpa antibody, rpa70 antibody, LOC100230990 antibody, 5031405K23Rik antibody, 70kDa antibody, AA589576 antibody, AW557552 antibody, Rpa antibody, CG9633 antibody, D-RPA70 antibody, D-SSB antibody, DRP-A antibody, DmRPA antibody, Dmel\\CG9633 antibody, RPA antibody, RPA 70 antibody, RPA 70 kDa antibody, RpA70 antibody, Rpa-70 antibody, Ssb-70 antibody, dRP-A antibody, dmrpa1 antibody, i164 antibody, replication protein A1 antibody, replication protein A1, 70kDa antibody, replication protein A1 L homeolog antibody, Replication Protein A 70 antibody, RPA1 antibody, Rpa1 antibody, rpa1 antibody, rpa1.L antibody, RpA-70 antibody
- Background
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RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. RPA1 binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing
Alias Symbols: HSSB, REPA1, RF-A, RP-A, RPA70, MST075
Protein Interaction Partner: STRA13, UBC, MTUS2, APITD1, PCNA, SUMO2, FBXO18, ATRX, MAP4, CAPRIN1, LMO7, LIG3, LDHA, ITGB1, IMPDH2, ILF3, ILF2, HSPB1, HSPA8, HSPA5, HNRNPU, HNRNPL, HNRNPK, HNRNPH1, HNRNPF, HNRNPD, HNRNPAB, HNRNPA2B1, HNRNPA1, HCFC1, GTF3C2, GTF2I, GTF2H3, GAPDH, XRCC
Protein Size: 616 - Molecular Weight
- 68 kDa
- Gene ID
- 6117
- NCBI Accession
- NM_002945, NP_002936
- UniProt
- P27694
- Pathways
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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