Kallikrein 7 antibody (Middle Region)

Catalog No. ABIN2787364

Product Details anti-Kallikrein 7 Antibody

Target: Kallikrein 7 (KLK7)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IKASKSFRHP GYSTQTHVND LMLVKLNSQA RLSSMVKKVR LPSRCEPPGT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against KLK7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KLK7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Kallikrein 7

Target: Kallikrein 7 (KLK7)

Alternative Name: KLK7 (KLK7 Products)

Synonyms: Prss6 antibody, SCCE antibody, PRSS6 antibody, hK7 antibody, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antibody, kallikrein-related peptidase 7 antibody, kallikrein related peptidase 7 antibody, Klk7 antibody, KLK7 antibody

Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis.
Protein Interaction Partner: APP, UBC, CDSN,
Protein Size: 181

Molecular Weight: 19 kDa

Gene ID: 5650

Pathways: Complement System