Caspase 7 antibody (N-Term)
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- Target See all Caspase 7 (CASP7) Antibodies
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Pig, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Goat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7
- Top Product
- Discover our top product CASP7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 336 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- Alternative Name
- CASP7 (CASP7 Products)
- Synonyms
- xCaspase-7 antibody, caspase-7 antibody, caspase7 antibody, cmh-1 antibody, ice-lap3 antibody, mch3 antibody, CASP7 antibody, AI314680 antibody, CMH-1 antibody, ICE-IAP3 antibody, Mch3 antibody, mCASP-7 antibody, CASP-7 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody, Caspase-7 antibody, MCH3/SCA-2 antibody, SCA-2 antibody, caspase 7 antibody, caspase-7 antibody, caspase 7 S homeolog antibody, CASP7 antibody, xcaspase-7 antibody, casp7 antibody, casp7.S antibody, Casp7 antibody
- Background
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: PTGES3, BAX, PARP1, SAT1, CRYAB, XIAP, RPS6KA1, CTSA, PEPD, MVD, GNS, GBP2, EEF2, CAPN1, CNDP2, GINS2, EIF4H, GZMB, ROCK1, DFFA, CASP9, CASP7, CASP3, ARHGDIA, VIM, STAT1, SPTAN1, CLSPN, PLA2G4B, RB1, UBC, BIRC2, CCT2, VCP, SP1, BIRC3, BIRC6, COPS6, TERF1,
Protein Size: 336 - Molecular Weight
- 37 kDa
- Gene ID
- 840
- NCBI Accession
- NM_033338, NP_203124
- UniProt
- P55210
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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