TNFSF4 antibody (Middle Region)
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- Target See all TNFSF4 Antibodies
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFSF4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QEVNISLHYQ KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TNFSF4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TNFSF4
- Top Product
- Discover our top product TNFSF4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 183 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- Alternative Name
- TNFSF4 (TNFSF4 Products)
- Synonyms
- TNFSF4 antibody, OX40L antibody, TNFRSF4 antibody, CD134L antibody, CD252 antibody, GP34 antibody, OX-40L antibody, OX4OL antibody, TXGP1 antibody, Ath-1 antibody, Ath1 antibody, Ox40l antibody, Txgp1l antibody, gp34 antibody, TNF superfamily member 4 antibody, tumor necrosis factor (ligand) superfamily, member 4 antibody, TNFSF4 antibody, Tnfsf4 antibody
- Background
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Alias Symbols: CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Protein Interaction Partner: TRAF2, TNFRSF4,
Protein Size: 183 - Molecular Weight
- 21 kDa
- Gene ID
- 7292
- NCBI Accession
- NM_003326, NP_003317
- UniProt
- P23510
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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