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TNFSF4 Products

(Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Categories

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq, Jul 2008].

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Featured TNFSF4 Categories

TNFSF4 Antibodies

High quality antibodies with extensive validation data.

TNFSF4 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFSF4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFSF4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, WB
Validations
  • (2)
Cat. No. ABIN655028
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application FACS, ELISA
Validations
  • (2)
Cat. No. ABIN7092913
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN740640
Quantity 100 μL
Datasheet Datasheet

Recommended TNFSF4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960262
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6974871
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1672818
Quantity 96 tests
Datasheet Datasheet

Recommended TNFSF4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275393
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6961094
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN2870675
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our TNFSF4 products

Upadhyaya, Lahdenranta, Hurov, Battula, Dods, Haines, Kleyman, Kristensson, Kublin, Lani, Ma, Mudd, Repash, Van Rietschoten, Stephen, You, Harrison, Chen, McDonnell, Brandish, Keen: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).

Yang, Yeh, Madireddi, Matochko, Gu, Pacheco Sanchez, Ultsch, De Leon Boenig, Harris, Leonard, Scales, Zhu, Christensen, Hang, Brezski, Marsters, Ashkenazi, Sukumaran, Chiu, Cubas, Kim, Lazar: "Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members." in: mAbs, Vol. 11, Issue 6, pp. 996-1011, (2020) (PubMed).

Sun, Chen, Wu, Dai, Wu: "TSLP-activated dendritic cells induce T helper type 2 inflammation in Aspergillus fumigatus keratitis." in: Experimental eye research, Vol. 171, pp. 120-130, (2018) (PubMed).

Fromm, de Silva, Johannes, Patel, Hornblower, Schreiber: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).

Chihara, Kagami, Kato, Yoshida, Kiyono, Okada, Kinoshita, Seto: "IL2/IL-4, OX40L and FDC-like cell line support the in vitro tumor cell growth of adult T-cell leukemia/lymphoma." in: Leukemia research, Vol. 38, Issue 5, pp. 608-12, (2014) (PubMed).

Byun, Ma, Akçay, Pedergnana, Palendira, Myoung, Avery, Liu, Abhyankar, Lorenzo, Schmidt, Lim, Cassar, Migaud, Rozenberg, Canpolat, Aydogan, Fleckenstein, Bustamante, Picard, Gessain, Jouanguy et al.: "Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. ..." in: The Journal of experimental medicine, Vol. 210, Issue 9, pp. 1743-59, (2013) (PubMed).

Zhang, Wu, Yang, Wang, Feng, Jiang, Zeng, Xu, Li, Jin, Lv, Zhang, Fu, Wang: "Upregulation of OX40 ligand on monocytes contributes to early virological control in patients with chronic hepatitis C." in: European journal of immunology, Vol. 43, Issue 7, pp. 1953-62, (2013) (PubMed).

Wang, Yi, Qin, Maldonado, von Andrian, Kulkarni, Tellides, Pober: "Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells." in: The Journal of clinical investigation, Vol. 123, Issue 4, pp. 1677-93, (2013) (PubMed).

Lei, Zhu, Zeng, Wang, Zhang, Chen, Mu, Huang: "SOX40L: an important inflammatory mediator in adult bronchial asthma." in: Annals of the Academy of Medicine, Singapore, Vol. 41, Issue 5, pp. 200-4, (2012) (PubMed).

Beynon, Quintana, Weiner: "Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling." in: PLoS ONE, Vol. 7, Issue 6, pp. e39576, (2012) (PubMed).

Synonyms and alternative names related to TNFSF4

TNF superfamily member 4 (TNFSF4), tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4), tumor necrosis factor (ligand) superfamily, member 4 (Tnfsf4), TNF superfamily member 4 (Tnfsf4), Ath-1, Ath1, CD134L, CD252, GP34, gp34, OX-40L, OX4OL, OX40L, Ox40l, TNFRSF4, TNFSF4, TXGP1, Txgp1l

Protein level used designations for TNFSF4

  • tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa)
  • tumor necrosis factor (ligand) superfamily, member 4
  • tumor necrosis factor ligand superfamily member 4
  • CD134(OX40)-ligand
  • OX40L protein
  • CD134 ligand
  • OX40 antigen ligand
  • OX40L
  • TAX transcriptionally-activated glycoprotein 1
  • glycoprotein Gp34
  • tax-transcriptionally activated glycoprotein 1 (34kD)
  • OX40 ligand
  • atherosclerosis 1
  • tax-transcriptionally activated glycoprotein 1 ligand
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