MAPKAP Kinase 2 antibody (Middle Region)
-
- Target See all MAPKAP Kinase 2 (MAPKAPK2) Antibodies
- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MAPKAP Kinase 2 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MAPKAPK2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MAPKAPK2
- Top Product
- Discover our top product MAPKAPK2 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 370 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
- Alternative Name
- MAPKAPK2 (MAPKAPK2 Products)
- Synonyms
- mapkapk2 antibody, wu:fb30e10 antibody, wu:fc56c10 antibody, wu:fi03a01 antibody, MGC78852 antibody, MAPKAPK2 antibody, AA960234 antibody, MAPKAP-K2 antibody, MK-2 antibody, MK2 antibody, Rps6kc1 antibody, mitogen-activated protein kinase-activated protein kinase 2a antibody, mitogen-activated protein kinase-activated protein kinase 2 L homeolog antibody, mitogen-activated protein kinase-activated protein kinase 2 antibody, MAP kinase-activated protein kinase 2 antibody, mapkapk2a antibody, mapkapk2.L antibody, MAPKAPK2 antibody, Mapkapk2 antibody
- Background
-
MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.
Alias Symbols: 3PK, MAPKAP3, MK2, MK-2, MAPKAP-K2
Protein Interaction Partner: PIAS2, DDX5, MAPK14, AKT1, HSPB1, MAPKAPK2, UBC, Ube2j1, TCF3, DES, MAP2K6, MAPK11, MAPK3, PABPC1, HNRNPA0, PARN, LIMK1, HSF1, CHEK1, CDC25B, ALOX5, ZFP36L1, ESR1, COPS5, CUL3, MAPKAPK5, MAPK1, ELAVL1, PHC2, CSNK2B, ARPC5, EEF2K, BAG2, YWHAZ, SRF, SHC1, E
Protein Size: 370 - Molecular Weight
- 42 kDa
- Gene ID
- 9261
- NCBI Accession
- NM_004635, NP_004626
- UniProt
- Q16644
- Pathways
- MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
-