HIST1H3A antibody (N-Term)
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- Target See all HIST1H3A Antibodies
- HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HIST1H3A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KQTARKSTGG KAPRKQLATK AARKSAPATG GVKKPHRYRP GTVALREIRR
- Predicted Reactivity
- Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HIST1H3A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HIST1H3A
- Top Product
- Discover our top product HIST1H3A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 136 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))
- Alternative Name
- HIST1H3A (HIST1H3A Products)
- Synonyms
- H3/A antibody, H3FA antibody, histone cluster 1 H3 family member a antibody, histone cluster 1, H3a antibody, HIST1H3A antibody, Hist1h3a antibody
- Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H3/A, H3FA, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
Protein Interaction Partner: WHSC1, SETD1A, FBLIM1, PRDM2, PRDM6, UBC, H2AFY, H2AFX, HIST1H1B, HIST1H1E, HIST1H1C, BAZ1B, HIST1H2AG, SMARCA5, HIST1H4A, HDAC2, UHRF1, L3MBTL2, GRB2, IRF1, HDAC11, AURKC, RPS6KA3, PAK1, ATXN1, ITGA4, env, CHAF1B, ASF1B, ASF1A, AURKB, CHAF1A, EP300, LRRK
Protein Size: 136 - Molecular Weight
- 15 kDa
- Gene ID
- 8350
- NCBI Accession
- NM_003529, NP_003520
- UniProt
- P68431
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