KLRC1 antibody (N-Term)
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- Target See all KLRC1 Antibodies
- KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLRC1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PKRQQRKPKG NKSSILATEQ EITYAELNLQ KASQDFQGND KTYHCKDLPS
- Predicted Reactivity
- Guinea Pig: 79%, Human: 100%, Mouse: 86%
- Characteristics
- This is a rabbit polyclonal antibody against KLRC1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product KLRC1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 233 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
- Alternative Name
- KLRC1 (KLRC1 Products)
- Synonyms
- rNKG2A antibody, NKG2-A antibody, NKG2A antibody, KLRC1 antibody, CD159A antibody, NKG2 antibody, CD159a antibody, NKG2B antibody, killer cell lectin like receptor C1 antibody, NKG2-A/NKG2-B type II integral membrane protein-like antibody, killer cell lectin-like receptor subfamily C, member 3 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, Klrc1 antibody, KLRC1 antibody, NKG2A antibody, KLRC3 antibody
- Background
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alias Symbols: CD159A, MGC13374, MGC59791, NKG2, NKG2A
Protein Interaction Partner: PMP22, MAL, KLRD1, PTPN6, PTPN11, HLA-E,
Protein Size: 233 - Molecular Weight
- 26 kDa
- Gene ID
- 3821
- NCBI Accession
- NM_002259, NP_002250
- UniProt
- P26715
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