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Angiopoietin 2 antibody (Middle Region)
ANGPT2
Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse, Sheep
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Angiopoietin 2 Antibody
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Target
See all Angiopoietin 2 (ANGPT2) Antibodies
Angiopoietin 2 (ANGPT2)
Binding Specificity
All epitopes for Angiopoietin 2 antibodies
Middle Region
Reactivity
Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse, Sheep
Host
All hosts for Angiopoietin 2 antibodies
Rabbit
Clonality
All clonalities for Angiopoietin 2 antibodies
Polyclonal
Conjugate
All conjugates for Angiopoietin 2 antibodies
This Angiopoietin 2 antibody is un-conjugated
Application
All applications for Angiopoietin 2 antibodies
Western Blotting (WB)
Sequence
NQTTRLELQL LQHSISTNKL EKQILDQTSE INKLQNKNSF LEQKVLDMEG
Predicted Reactivity
Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
Characteristics
This is a rabbit polyclonal antibody against Angpt2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Mouse Angpt2
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Discover our top product ANGPT2 Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Angiopoietin 2
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Target
Angiopoietin 2 (ANGPT2)
Alternative Name
Angpt2 (ANGPT2 Products )
Synonyms
AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
Background
Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Alias Symbols: Agpt2, Ang-2, Ang2 Protein Size: 496
Molecular Weight
56 kDa
Gene ID
11601
NCBI Accession
NM_007426 , NP_031452
UniProt
O35608
Pathways
RTK Signaling
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